Highlighted publications
McCormack, N.M., Calabrese, K.A., Sun, C.M., Tully, C.B., Heier, C.R., and Fiorillo, A.A. Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping. Molecular Therapy - Nucleic Acids 35. 2024. PMID: 38975000 PMCID: PMC1122584​
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Oliver, T., Nguyen, N.Y., Tully, C.B., McCormack, N.M., Sun, C.M., Fiorillo, A.A., and Heier, C.R. The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease. Dis Model Mech 17. 2024. PMID: 38770680 PMCID: PMC11139035
McCormack NM, Nguyen NY, Tully CB, Oliver T, Fiorillo AA, Heier CR. Vamorolone improves Becker muscular dystrophy and increases dystrophin protein in bmx model mice. iScience. 2023;26:107161. PMID: 37534133 PMCID: PMC10391915
Heier, C. R.; McCormack, N. M.; Tully, C. B.; Novak, J. S.; Newell-Stamper, B. L.; Russell, A. J.; Fiorillo, A. A., The X-linked Becker muscular dystrophy (bmx) mouse models Becker muscular dystrophy via deletion of murine dystrophin exons 45-47. J Cachexia Sarcopenia Muscle 2023. PMID: 36628607
Kinder TB, Heier CR, Tully CB, Van der Muelen JH, Hoffman EP, Nagaraju K, Fiorillo AA. Muscle Weakness in Myositis: MicroRNA-Mediated Dystrophin Reduction in a Myositis Mouse Model and Human Muscle Biopsies. Arthritis Rheumatol. 2020 Jul;72(7):1170-1183. PMID: 32009304 PMCID: PMC7384101
Fiorillo AA, Heier CR, Huang YF, Tully CB, Punga T, Punga AR. Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs. Front Immunol. 2020;11:151. PMID: 32153563 PMCID: PMC7046803.
Heier CR, Yu Q, Fiorillo AA, Tully CB, Tucker A, Mazala DA, Uaesoontrachoon K, Srinivassane S, Damsker JM, Hoffman EP, Nagaraju K, Spurney CF. Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy. Life Sci Alliance. 2019 Feb;2(1). PMID: 30745312; PMCID: PMC6371196.
Novak JS, Hogarth MW, Boehler JF, Nearing M, Vila MC, Heredia R, Fiorillo AA, Zhang A, Hathout Y, Hoffman EP, Jaiswal JK, Nagaraju K, Cirak S, Partridge TA. Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle. Nat Commun. 2017 Oct 16;8(1):941. PMID: 29038471 PMCID: PMC5643396.
Fiorillo AA, Tully CB, Damsker JM, Nagaraju K, Hoffman EP, Heier CR. Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone. Physiol Genomics. 2018 Sep 1;50(9):735-745. PMID: 29883261 PMCID: PMC6172612. **Chosen for cover
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Fiorillo AA, Heier CR, Novak JS, Tully CB, Brown KJ, Uaesoontrachoon K, Vila MC, Ngheim PP, Bello L, Kornegay JN, Angelini C, Partridge TA, Nagaraju K, Hoffman EP. TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy. Cell Rep. 2015 Sep 8;12(10):1678-90. PMID: 26321630 PMCID: PMC4757433.
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Link to all publications: https://www.ncbi.nlm.nih.gov/myncbi/alyson.fiorillo.1/bibliography/public/